Epitome of the Pharmacopeia of the United States and the National Formulary Part 70

White, odorless, very bitter, silky needles. Soluble in water (1:18) and very soluble in alcohol (1:0.8).

ACTION AND USES: Has the action of other quinine salts; frequently preferred to the sulphate, because neutral and more soluble.

DOSAGE: Tonic, 0.1 Gm. or 1-1/2 grains (U.S.P.); antimalarial, at least 1 Gm. or 15 grains daily (U.S.P.).

_Syrupus Phosphatum c.u.m Quinina et Strychnina (Syr. Phosphat. c. Quin.

et Strych.), Syrup of Phosphates with Quinine and Strychnine, N.F._ (Syrupus Hydrochlorophosphatum, N.F. III, Compound Syrup of Hydrochlorophosphates).--Quinine hydrochloride (0.44%), strychnine nitrate (0.014%), compound solution of phosphates (50%) in glycerin and syrup.

DOSAGE: 4 Cc. or 1 fluidrachm (N.F.)

=Quininae Hypophosphis (Quin. Hypophos.), Quinine Hypophosphite, N.F.=

Fine, white, odorless crystals, with a very bitter taste.

ACTION AND USES: Superfluous quinine salt.

DOSAGE: Tonic, 0.1 Gm. or 1-1/2 grains (N.F.); antimalarial, 1 Gm. or 15 grains daily (N.F.)

=Quininae Salicylas (Quin. Salicyl.), Quinine Salicylate, U.S.P.=

Colorless (often becoming pinkish), odorless, bitter needles.

Soluble in alcohol (1:14) and in glycerin (1:13). Only slightly soluble in water.

ACTION AND USES: Superfluous; see Quininae Hydrochloridum.

The quant.i.ty of salicylate in a dose is usually too small to be effective.

DOSAGE: Tonic, 0.1 Gm. or 1-1/2 grains (U.S.P.); antimalarial, at least 1 Gm. or 15 grains daily (U.S.P.)

=*Quininae Sulphas (Quin. Sulph.), Quinine Sulphate, U.S.P.=

White, odorless, very bitter, efflorescent crystals. Slightly soluble in water (1:725) and in alcohol (1:107).

ACTION AND USES: The most commonly used quinine salt but inferior to the hydrochloride, the dihydrochloride and quinine and urea hydrochloride where a soluble salt is desired, and to the alkaloid or the tannate where an insoluble one is needed.

DOSAGE: Tonic, 0.1 Gm. or 1-1/2 grains (U.S.P.); antimalarial, at least 1 Gm. or 15 grains daily (U.S.P.).

_Elixir Cinchonae Alkaloidorum (Elix. Cinchon. Alk.), Elixir of Cinchona Alkaloids, N.F. (Elixir Cinchonae, N.F._ III, Elixir Calisaya, Alkaloidal).--Quinine sulphate (0.2%), cinchonidine sulphate (0.1%), cinchonine sulphate (0.1%), compound tincture of cudbear and aromatic elixir. Absolute alcohol content about 21 per cent.

USES: Imitation of cinchona, minus the tannin. No advantage over quinine.

DOSAGE: 8 Cc. or 2 fluidrachms (N.F.).

_Elixir Cinchonae Alkaloidorum et Hypophosphitum (Elix. Cinchon. et Hypophos.), Elixir of Cinchona Alkaloids and Hypophosphites, N.F._ (Elixir Cinchonae et Hypophosphitum, N.F. III, Elixir of Calisaya, Alkaloidal, with Hypophosphites).--Calcium hypophosphite and sodium hypophosphite (each 1.75%), elixir of cinchona alkaloids (about 85%), hypophosphorous acid and water. Absolute alcohol content about 18 per cent.

DOSAGE: 8 Cc. or 2 fluidrachms (N.F.).

_Elixir Cinchonae Alkaloidorum, Ferri et Calcii Lactophosphatis._--See under Calcii Lactophosphas.

_Pilulae Antiperiodicae (Pil. Antiperiod.), Antiperiodic Pills, N.F._ (Warburg's Pills).--Each pill contains quinine sulphate (0.09 Gm. or 1-1/2 grains), extract of aloes (0.065 Gm. or 1 grain) and rhubarb (0.032 Gm. or 1/2 grain) with angelica fruit, elecampane, saffron, fennel, zedoary, cubeb, myrrh, agaric, camphor and extract of gentian.

DOSAGE: 1 pill (N.F.).

_Pilulae Antiperiodicae sine Aloe (Pil. Antiperiod. s. Aloe), Antiperiodic Pills without Aloes, N.F._ (Warburg's Pills without Aloes).--Each pill contains quinine sulphate (0.09 Gm. or 1-1/2 grains), rhubarb (0.032 Gm. or 1/2 grain) with angelica fruit, elecampane, saffron, fennel, zedoary, cubeb, myrrh, agaric, camphor and extract of gentian.

DOSAGE: 1 pill (N.F.).

=*Quininae Tannas (Quin. Tann.), Quinine Tannate, U.S.P.=

Pale yellow, or yellowish-white, odorless and tasteless, or nearly tasteless powder. Only very slightly soluble in water. Somewhat more soluble in alcohol.

ACTION AND USES: Used where comparatively tasteless preparations are wanted.

DOSAGE: 0.2 Gm. or 3 grains (U.S.P.); sometimes administered with chocolate or sugar.

_Trochisci Quininae Tannatis (Troch. Quin. Tan.), Troches of Quinine Tannate, N.F._--Each troche contains quinine tannate (0.06 Gm. or 1 grain) with tragacanth, oil of theobroma, cocoa, sugar and sodium benzosulphinide.

DOSAGE: 1 troche (N.F.)

=Quininae Valeras (Quin. Valer.), Quinine Valerate, N.F.=

White, l.u.s.trous crystals, with a valerian-like odor and an intensely bitter taste.

ACTION AND USES: Those of quinine and valerates, but disagreeable and superfluous.

DOSAGE: Tonic, 0.1 Gm. or 1-1/2 grains (N.F.); antimalarial, 1 Gm. or 15 grains daily (N.F.).

_Elixir Quininae Valeratis et Strychninae (Elix. Quin. Valer. et Strych.), Elixir of Quinine Valerate and Strychnine, N.F._ (Elixir Quininae Valerianatis et Strychninae, N.F. III).--Quinine valerate (1.75%), strychnine sulphate (0.0175%), compound tincture of cudbear, distilled water and aromatic elixir. Absolute alcohol content about 22 per cent.

USES: Irrational "tonic" mixture.

DOSAGE: 4 Cc. or 1 fluidrachm (N.F.).

=Renninum (Rennin.), Rennin, N.F.=--Milk-curdling enzyme from the stomach of the calf.

Grayish-white or yellowish-white powder or yellowish grains or scales, with a characteristic, slightly saline taste and a peculiar odor. Slowly soluble in water and in diluted alcohol.

ACTION AND USES: For making wheys and junkets

=Resina (Resin.), Rosin, U.S.P.= (Colophony).--The residue left after distilling the volatile oil from turpentine (the oleoresin).