Epitome of the Pharmacopeia of the United States and the National Formulary Part 86

Large, colorless, translucent crystals, having an aromatic thyme-like odor, and a pungent, aromatic taste. Very slightly soluble in water (1:1,010); freely soluble in alcohol (1:1).

ACTION AND USES: Antiseptic and anthelmintic. Used chiefly against the hookworm.

DOSAGE: Antiseptic, 0.125 Gm. or 2 grains (U.S.P.); anthelmintic, 1 Gm. or 15 grains, per day (U.S.P.). In the treatment of hookworm disease it should be given in as finely divided state as possible in dosage of from 0.5 to 4 Gm. or from 8 grains to 1 drachm. No fats, oils or alcohol should be given at the same time, for fear of absorption of the drug.

The dosage may be regulated according to age as follows: Up to 5 years of age, 0.5 Gm. or 8 grains; up to 10, 1 Gm. or 15 grains; up to 15, 1.5 Gm. or 24 grains; up to 20, 2 Gm. or 30 grains; above 20, 3 to 4 Gm. or 45 grains to 1 drachm.

_Nebula Thymolis (Nebul. Thymol.), Thymol Spray, N.F._--Thymol (1%) in light liquid petrolatum.

=*Thymolis Iodidum (Thymol. Iod.), Thymol Iodide, U.S.P.= (Aristol).--Chiefly dithymol-diiodide. Should contain not less than 43 per cent. of iodine.

A reddish-brown or reddish-yellow, bulky powder, with a very slight aromatic odor. Insoluble in water or glycerin; only slightly soluble in alcohol.

ACTION AND USES: Antiseptic; used chiefly as a dusting powder. Less efficient than iodoform.

=Thymus (Thymus), Thyme, N.F.=--Tops.

ACTION AND USES: Aromatic and rubefacient; without advantage over camphor.

DOSAGE: 4 Gm. or 1 drachm (N.F.).

_Fluidextractum Thymi (Fldext. Thym.), Fluidextract of Thyme, N.F._--Thyme (100%). Absolute alcohol content about 20 per cent.

DOSAGE: 4 Cc. or 1 fluidrachm (N.F.).

=*Thyroideum Sicc.u.m (Thyroid. Sicc.), Dried Thyroids, U.S.P.= (Glandulae Thyroideae Siccae, U.S.P., VIII, Desiccated Thyroid Glands).--The thyroid glands of animals which are used for food by man, freed from connective tissue and fat, dried and powdered. Should contain about 0.2 per cent. of iodine.

A yellowish powder, with a slight characteristic odor.

ACTION AND USES: Used in thyroid deficiency; sometimes in obesity, in which it may be harmful.

DOSAGE: 0.1 Gm. or 1-1/2 grains (U.S.P.).

=TINCTURAE, TINCTURES.=--Tinctures with few exceptions are alcoholic or hydroalcoholic extractive preparations of vegetable drugs. The tinctures of potent drugs represent uniformly 10 Gm. of drug in 100 Cc. of the preparation, while tinctures of less potent drugs vary in strength but represent usually 20 Gm. of drug in 100 Cc. of the preparation. For the official tinctures see under the names of the respective drugs. For Tinctura Amara, see under =Gentiana=; for Tinctura Antiperiodica and Tinctura Antiperiodica sine Aloe, under =Quininae Bisulphas=; for Tinctura Aromatica, under =Cinnamomum Saigonic.u.m=; for Tinctura Ipecacuanhae et Opii and for Tinctura Pectoralis, under =Opium=.

=TINCTURAE AETHEREAE, ETHEREAL TINCTURES, N.F.=--When not otherwise directed, ethereal tinctures are to be prepared representing 10 per cent. drug strength, extracted with a mixture of alcohol and ether. Of doubtful advantage over ordinary tinctures.

=TINCTURAE MEDICAMENTORUM RECENTIUM, TINCTURES OF FRESH DRUGS, N.F.= (Tincturae Herbarum Recentium, U.S.P. VIII).--When not otherwise directed, tinctures of fresh drugs are to be prepared by extracting 50 Gm. of the fresh drug with alcohol to make 100 Cc.

=TOXITABELLAE, POISON TABLETS.=--Tablets containing poisons.

=*Tragacantha (Trag.), Tragacanth, U.S.P.= (Gum Tragacanth).--Mixed with 50 parts of distilled water, forms a smooth, nearly uniform, stiff, opalescent mucilage.

ACTION AND USES: Demulcent and ingredient in emulsions.

_Glyceritum Tragacanthae (Glycer. Trag.), Glycerite of Tragacanth, N.F._--Tragacanth (about 10%) in glycerin and water.

_Mucilago Tragacanthae (Mucil. Trag.), Mucilage of Tragacanth, U.S.P._--Tragacanth (6%) in glycerin (18%) and water.

=Trifolium (Trifol.), Trifolium, N.F.= (Red Clover Blossoms).

ACTION AND USES: Inert. Has been used in antisyphilitic and alterative compounds; also as an expectorant.

DOSAGE: 4 Gm. or 1 drachm (N.F.).

_Fluidextractum Trifolii (Fldext. Trifol.), Fluidextract of Trifolium, N.F._--Trifolium (100%). Absolute alcohol content about 40 per cent.

DOSAGE: 4 Cc. or 1 fluidrachm (N.F.).

=Trillium (Trill.), Trillium, N.F.= (Beth Root).--Rhizome.

ACTION AND USES: Obsolete, formerly used as astringent and tonic.

DOSAGE: 2 Gm. or 30 grains (N.F.).

_Fluidextractum Trillii (Fldext. Trill.), Fluidextract of Trillium, N.F._--Trillium (100%). Absolute alcohol content about 60 per cent.

DOSAGE: 2 Cc. or 30 minims (N.F.).

=*Trinitrophenol (Trinitrophen.), Trinitrophenol, U.S.P.= (Picric Acid).

Pale yellow, odorless crystals, having an intensely bitter taste, and exploding when heated rapidly and when subjected to percussion.

Trinitrophenol stains the skin an intense, permanent yellow.

Soluble in water (1:78), and in alcohol (1:12).

ACTION AND USES: For the dressing of burns. Internally is highly toxic, producing nausea, vomiting and diarrhea, and stains the skin and mucous membranes a yellow color, simulating jaundice.

DOSAGE: Externally as saturated watery solution or as ointment.

=Tritic.u.m (Tritic.), Tritic.u.m, U.S.P.= (Couch Gra.s.s, Dog Gra.s.s).--Rhizome and roots.

ACTION AND USES: Formerly exploited as a diuretic in cyst.i.tis and irritable bladder. Now seldom employed.

DOSAGE: 8 Gm. or 2 drachms (U.S.P.).

_Fluidextractum Tritici (Fldext. Tritic.), Fluidextract of Tritic.u.m, U.S.P._ (Fluidextract of Couch Gra.s.s).--Tritic.u.m (100%). Absolute alcohol content about 15 per cent.